B12 is essential for red blood cell formation, DNA synthesis, and the proper functioning of the nervous system. It's also a cofactor in producing serotonin and dopamine. Deficiency causes fatigue, brain fog, depression, numbness & if untreated irreversible nerve damage. Our methylcobalamin form is the most bioavailable and neurologically active form available. Groups at highest risk: vegans, over 50s, those on metformin or PPIs, and anyone with Crohn's, IBS or coeliac disease.

Vitamin D is technically a hormone with receptors in virtually every cell. It regulates immunity, mood, muscle strength, cardiovascular health and hormone production. Oral absorption is inconsistent and depends on adequate fat intake, NHS testing regularly finds deficiency in patients taking standard supplements. In the North East, limited sunlight for much of the year makes deficiency extremely common. A single IM injection raises and sustains levels for months.

Glutathione is produced in every cell and is the liver's primary detoxification tool, neutralising free radicals, protecting DNA, supporting the immune response and inhibiting melanin overproduction (brightening skin tone).

It depletes with age, stress, illness and alcohol. Oral glutathione is almost entirely broken down in the gut before reaching the bloodstream. IM and IV delivery are the only effective routes.

Biotin is essential for keratin synthesis, the structural protein that forms hair, nails and skin. Many people with hair thinning have low or suboptimal biotin.

The problem is that oral biotin is poorly absorbed by those with gut conditions, or blocked by avidin in raw eggs. IM biotin bypasses this entirely. Visible improvements in hair thickness and nail strength typically build over a course of 4–6 monthly injections.